所有产品

cAMP/ cGMP/ Protein A/ β-Actin/ BSA/ Ddx4/ APOE/ TAU pT181/ TAU pT217/ Tau 1-441/ Aβ1-40/ Aβ1-42/ α-Syn/ GFAP/ IL/ CD/ 标记试剂盒/ GFP/ Flag/ 多肽合成服务/ /

抗体药类似物

产品中心

Product Center

Research Grade Mosunetuzumab

All

TD-HY257166_1.jpg

TD-HY257166_2.jpg

TD-HY257166_3.jpg

详细相关信息

FAQ

实验方案

Research Grade Mosunetuzumab

Catalog No.	TD-HY257166
Species reactivity	Human
Applications	Research Grade Biosimilar
Host species	Humanized
Isotype	IgG1-kappa
Expression system	Mammalian Cells
Species	Human
Clonality	Monoclonal
Target	B-lymphocyte surface antigen B1, Membrane-spanning 4-domains subfamily A member 1, MS4A1, Leukocyte surface antigen Leu-16, B-lymphocyte antigen CD20, Bp35, CD20, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P11836 & P07766
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternate Names	Bispecific, BTCT4465A, RG-7828, RO7030816, CAS: 1905409-39-3
Background	Mosunetuzumab (BTCT-4465A) is a full-length, fully humanized immunoglobulin G1 (IgG1) T-cell-dependent bispecific (TDB) antibody targeting CD20 (B cells) and CD3 (T cells). Mosunetuzumab redirects T cells to engage and eliminate malignant B cells and can be used for the research of relapsed or refractory (R/R) B-cell non-Hodgkin lymphomas (B-NHLs).
Note	For research use only. Not suitable for clinical or therapeutic use.

SDS-PAGE	SDS-PAGE for Research Grade Mosunetuzumab.
Bioactivity	Detects Human CD20/MS4A1 & CD3E separately in indirect ELISAs.
Bioactivity	Detects Human CD20/MS4A1 & CD3E separately in indirect ELISAs.