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抗体药类似物
Research Grade Epcoritamab
All
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  • CatalogTD-HY257136
  • ClonalitymAb
  • Application Research Grade Biosimilar
  • SynonymsGEN3013, CAS: 2134641-34-0
  • 规格
    1mg
  • 价格
    ¥询价
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Research Grade Epcoritamab


Catalog No. TD-HY257136
Species reactivity Human
Applications Research Grade Biosimilar
Host species Chimeric
Isotype Ig(G1-kappa_G1-lambda)
Expression system Mammalian Cells
Species Human
Clonality Monoclonal
Target B-lymphocyte surface antigen B1, Membrane-spanning 4-domains subfamily A member 1, MS4A1, Leukocyte surface antigen Leu-16, B-lymphocyte antigen CD20, Bp35, CD20, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P11836 & P07766
Form Liquid
Storage buffer 0.01M PBS, pH 7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternate Names GEN3013, CAS: 2134641-34-0
Background Epcoritamab (GEN3013) is an bispecific IgG1 antibody redirecting T-cells toward CD3×CD20+ tumor cells. Epcoritamab induces potent T-cell-mediated cytotoxicity towards B-cell NHL cell lines.
Note For research use only. Not suitable for clinical or therapeutic use.

 

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Bioactivity
 
Detects CD3E in indirect ELISAs.
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SDS-PAGE
 
SDS-PAGE for Research Grade Epcoritamab.