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抗体药类似物
Research Grade Ocaratuzumab
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  • CatalogTD-HY257126
  • ClonalitymAb
  • Application Research Grade Biosimilar
  • SynonymsAME-133v, LY2469298, CAS: 1169956-08-4
  • 规格
    1mg
  • 价格
    ¥询价
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Research Grade Ocaratuzumab


Catalog No. TD-HY257126
Species reactivity Human
Applications Research Grade Biosimilar
Host species Humanized
Isotype IgG1-kappa
Expression system Mammalian Cells
Species Human
Clonality Monoclonal
Target B-lymphocyte surface antigen B1, Membrane-spanning 4-domains subfamily A member 1, MS4A1, Leukocyte surface antigen Leu-16, B-lymphocyte antigen CD20, Bp35, CD20
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P11836
Form Liquid
Storage buffer 0.01M PBS, pH 7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternate Names AME-133v, LY2469298, CAS: 1169956-08-4
Background Ocaratuzumab (AME 133v) is an Fc-engineered humanized IgG1 anti-CD20 monoclonal antibody, with a Kd of ~100 pM. Ocaratuzumab exhibits more effective antibody-dependent cell-mediated cytotoxicity (ADCC).
Note For research use only. Not suitable for clinical or therapeutic use.

 

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Bioactivity
 
Detects Human CD20/MS4A1 in indirect ELISAs.
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SDS-PAGE
 
SDS-PAGE for Research Grade Ocaratuzumab.