EN
抗体药类似物
Research Grade Abelacimab
All
TD-HY171026_1.jpg
TD-HY171026_2.jpg
TD-HY171026_3.jpg
  • CatalogTD-HY171026
  • ClonalitymAb
  • Application Research Grade Biosimilar
  • SynonymsNVS250519,CAS:2098724-83-3,FXI,FXIa,
  • 规格
    1mg
  • 价格
    ¥询价
定制服务咨询

Research Grade Abelacimab


Catalog No. TD-HY171026
Species reactivity Human
Applications Research Grade Biosimilar
Host species Human
Isotype IgG1-lambda
Expression system Mammalian Cells
Clonality Monoclonal
Target Plasma thromboplastin antecedent, PTA, Coagulation factor XI, F11, FXI
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G, purified from cell culture supernatant.
Accession P03951
Form Liquid
Storage buffer 0.01M PBS,pH7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names NVS250519,CAS:2098724-83-3,FXI,FXIa,
Background Abelacimab (MAA868) is a fully human IgG1 monoclonal antibody that binds with high affinity to the catalytic structural domain of FXI and locks it in the zymogen conformation, thereby preventing its activation by FXIIa or thrombin. Abelacimab can be used in thromboembolic disease studies.
Note For research use only. Not for use in clinical or therapeutic applications.

 

TD-HY171026_1.jpg
SEC-HPLC
 
SEC-HPLC detection for Research Grade Abelacimab.
TD-HY171026_2.jpg
Bioactivity
 
Detects F11 in indirect ELISAs.
TD-HY171026_3.jpg
SDS-PAGE
 
SDS-PAGE for Research Grade Abelacimab.