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抗体药类似物
Research Grade Xentuzumab
All
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  • CatalogTD-HY095016
  • ClonalitymAb
  • Application Research Grade Biosimilar
  • SynonymsBI 836845, CAS: 1417158-65-6
  • 规格
    1mg
  • 价格
    ¥询价
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Research Grade Xentuzumab


Catalog No. TD-HY095016
Species reactivity Human
Applications Research Grade Biosimilar
Host species Humanized
Isotype IgG1-lambda
Expression system Mammalian Cells
Species Human
Clonality Monoclonal
Target IGF-I, IGF1, Mechano growth factor, MGF, Insulin-like growth factor I, IBP1, Somatomedin-C, IGF2, IGF-II, Insulin-like growth factor II, T3M-11-derived growth factor, Somatomedin-A
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P05019 & P01344
Form Liquid
Storage buffer 0.01M PBS, pH 7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternate Names BI 836845, CAS: 1417158-65-6
Background Xentuzumab (Anti-Human IGF1 and IGF2 Recombinant Antibody; BI836845) is a recombinant a human monoclonal antibody that targets IGF ligands IGF1 and IGF2. Xentuzumab inhibits both of IGF1 and IGF2 growth-promoting signalling and suppresses AKT activation.
Note For research use only. Not suitable for clinical or therapeutic use.

 

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Bioactivity
 
Detects IGF1 in indirect ELISAs.
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SDS-PAGE
 
SDS-PAGE for Research Grade Xentuzumab.