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Research Grade Abituzumab
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- Catalog： TD-HY065016
- Clonality： mAb
- Application： Research Grade Biosimilar
- Synonyms： DI-17E6,EMD525797,CAS:1105038-73-0
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规格：
1mg
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价格：
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Research Grade Abituzumab
| Catalog No. | TD-HY065016 |
|---|---|
| Species reactivity | Human |
| Applications | Research Grade Biosimilar |
| Host species | Humanized |
| Isotype | IgG2-kappa |
| Expression system | Mammalian Cells |
| Clonality | Monoclonal |
| Target | MSK8, VNRA, Vitronectin receptor, Integrin alpha-V, Vitronectin receptor subunit alpha, CD51, ITGAV, VTNR |
| Endotoxin level | Please contact the lab for this information. |
| Purity | >95% purity as determined by SDS-PAGE. |
| Purification | Protein A/G, purified from cell culture supernatant. |
| Accession | P06756 |
| Form | Liquid |
| Storage buffer | 0.01M PBS,pH7.4. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Alternate Names | DI-17E6,EMD525797,CAS:1105038-73-0 |
| Background | Abituzumab (DI17E6) is a humanised anti-integrin αV monoclonal antibody (IgG2 type). Abituzumab effectively reduces the phosphorylation of FAK, Akt and ERK. Abituzumab can be used in cancer research, particularly in prostate cancer. |
| Note | For research use only. Not for use in clinical or therapeutic applications. |
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SEC-HPLC detection for Research Grade Abituzumab. |
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Flow-cytometry using anti-human CD51 antibody. A549 cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD51 monoclonal antibody (Catalog HY065016, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer. |
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SDS-PAGE for Research Grade Abituzumab. |