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抗体药类似物
Research Grade Astegolimab
All
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  • CatalogTD-HX139016
  • ClonalitymAb
  • Application Research Grade Biosimilar
  • SynonymsAMG-282,MSTT-1041A,RG-6149,RO-7187807,CAS:2173054-79-8
  • 规格
    1mg
  • 价格
    ¥询价
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Catalog No. TD-HX139016
Species reactivity Human
Applications Research Grade Biosimilar
Host species Human
Isotype IgG2-kappa
Expression system Mammalian Cells
Clonality Monoclonal
Target T1, DER4, Interleukin-1 receptor-like 1, ST2, IL1RL1, Protein ST2
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G, purified from cell culture supernatant.
Accession Q01638
Form Liquid
Storage buffer 0.01M PBS,pH7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names AMG-282,MSTT-1041A,RG-6149,RO-7187807,CAS:2173054-79-8
Background Astegolimab (MSTT 1041A; RG 6149) is a human IgG2 monoclonal antibody that blocks IL-33 signaling by targeting ST2, the IL-33 receptor. Astegolimab has the potential for chronic obstructive pulmonary disease (COPD) research.
Note For research use only. Not for use in clinical or therapeutic applications.

 

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SEC-HPLC
 
SEC-HPLC detection for Research Grade Astegolimab.
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Bioactivity
 
Detects Human IL1RL1/ST2 in indirect ELISAs.