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抗体药类似物
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Research Grade Gresonitamab
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SDS-PAGE
Flow cytometry
  • Catalog： TD-HX126026
  • Clonality： Monoclonal
  • Application： ELISA, Bioactivity: FACS, Functional assay, Research in vivo
  • Synonyms： Bispecific, AMG910, AMG-910, AMG9102413817-97-5
  • 规格：
    询价
  • 价格：
    ¥100ug
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  • Catalog No.
    TD-HX126026
  • Description
    Gresonitamab(TD-HX126026) is a research-grade recombinant antibody targetingCD3. Produced in mammalian cells with native-like glycosylation.HighlightsResearch Grade— For PK/PD studies, assay development, and ADA research.Native Glycosylation— Mammalian expression ensures native-like patterns.
  • Species reactivity
    Human
  • Applications
    ELISA, Bioactivity: FACS, Functional assay, Research in vivo
  • Host species
    Humanized
  • Isotype
    (scFv-heavy-kappa)-(scFv-heavy-lambda)-scFc
  • Clonality
    Monoclonal
  • Target
    Claudin-18, CLDN18, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain
  • Endotoxin level
    Please contact the lab for this information.
  • Purity
    >95% purity as determined by SDS-PAGE.
  • Purification
    Protein A/G purified from cell culture supernatant.
  • Accession
    P56856-2 & P07766
  • Form
    Liquid
  • Storage buffer
    0.01M PBS, pH 7.4.Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
  • Stability and Storage
    Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
  • Alternate Names
    Bispecific, AMG910, AMG-910, AMG9102413817-97-5
  • Background
    Gresonitamab (AMG 910) is a half-life extended (HLE) bispecific T-cell engager (BiTE) antibody targets CD3-positive T cells and CLDN18.2-expressing tumor cells. Gresonitamab can be used for the research of adenocarcinoma.
  • Caption
    SDS-PAGE for Research Grade Gresonitamab　　|　Flow-cytometry APC using anti-human CLDN18.2 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an APC anti-human CLDN18.2 monoclonal antibody (Catalog HX126026) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.
  • Note
    For research use only. Not suitable for clinical or therapeutic use.