Zilovertamab(TD-HX065016) is a research-grade recombinant antibody targetingNeurotrophic tyrosine kinase. Produced in mammalian cells with native-like glycosylation.HighlightsResearch Grade— For PK/PD studies, assay development, and ADA research.Native Glycosylation— Mammalian expression ensures native-like patterns.
Species reactivity
Human
Applications
ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Protein A/G purified from cell culture supernatant.
Accession
Q01973
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names
cirmtuzumab, 2485779-13-1
Background
Zilovertamab (UC-961) is a humanised monoclonal antibody against ROR1 that blocks Wnt5a-induced ROR1 signalling.• Structural Insights into Pseudokinase Domains of Receptor Tyrosine Kinases., PMID:32619402• SETD8 induces stemness and epithelial-mesenchymal transition of pancreatic cancer cells by regulating ROR1 expression., PMID:34599596• Cross-talk among ROR alpha 1 and the Rev-erb family of orphan nuclear receptors., PMID:7838158
Caption
SEC-HPLC detection for Research Grade Zilovertamab. | Detects ROR1 in indirect ELISAs. | Western blot analysis was performed using anti-ROR1 monoclonal antibody at 1ug/mL on various samples.Lane 1:recombinant human ROR1 (Catalog No:TD-HX065011)Lane 2:negative control
Note
For research use only. Not suitable for clinical or therapeutic use.
抗体
试剂盒
多肽
蛋白
组织芯片
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