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抗体药类似物
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Research Grade Belatacept
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SDS-PAGE
  • Catalog： TD-HW630026
  • Clonality：
  • Application： ELISA, Functional assay, Research in vivo
  • Synonyms： BMS-224818, LEA29Y, 706808-37-9
  • 规格：
    询价
  • 价格：
    ¥100ug
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  • Catalog No.
    TD-HW630026
  • Description
    Belatacept(TD-HW630026) is a research-grade recombinant antibody targetingCD80. Produced in mammalian cells with native-like glycosylation.HighlightsResearch Grade— For PK/PD studies, assay development, and ADA research.Native Glycosylation— Mammalian expression ensures native-like patterns.
  • Species reactivity
    Human
  • Applications
    ELISA, Functional assay, Research in vivo
  • Isotype
    Fusion - [CTLA4 (cytotoxic T-lymphocyte-associated protein 4, CD152)]2 - IGHG1 Fc (Fragment constant)
  • Target
    CD80, BB1, T-lymphocyte activation antigen CD80, CD28LG, B7, CD28LG1, LAB7, Activation B7-1 antigen, CTLA-4 counter-receptor B7.1, BU63, B70, CD28LG2, CTLA-4 counter-receptor B7.2, Activation B7-2 antigen, T-lymphocyte activation antigen CD86, CD86, FUN-1
  • Endotoxin level
    Please contact the lab for this information.
  • Purity
    >95% purity as determined by SDS-PAGE.
  • Purification
    Protein A/G purified from cell culture supernatant.
  • Accession
    P33681 & P42081
  • Form
    Liquid
  • Storage buffer
    0.01M PBS, pH 7.4.Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
  • Stability and Storage
    Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
  • Alternate Names
    BMS-224818, LEA29Y, 706808-37-9
  • Background
    Belatacept (BMS 224818) is a selective T-cell costimulation blocker and a costimulator of the CD28-CD80/86 pathway. Belatacept binds to the CD 80/86 ligand and inhibits CD-28-mediated T cell costimulation and IFN-γ production. Belatacept can be used in studies of immunosuppression in organ transplantation.
  • Caption
    SDS-PAGE for Research Grade Belatacept
  • Note
    For research use only. Not suitable for clinical or therapeutic use.