Background
Eurestobart is a humanized IgG1κ antibody targeting ENTPDase.• CD39 and CD73 in immunity and inflammation., PMID:23601906• Ectonucleoside triphosphate diphosphohydrolase-1 (CD39) impacts TGF-β1 responses: insights into cardiac fibrosis and function following myocardial infarction., PMID:36240436• Favorable function of Ectonucleoside triphosphate diphosphohydrolase 1 high expression in thyroid carcinoma., PMID:34465393• Ectonucleoside triphosphate diphosphohydrolase-1 (E-NTPDase1/CD39) as a new prognostic marker in chronic lymphocytic leukemia., PMID:24684231• Revealing and harnessing CD39 for the treatment of colorectal cancer and liver metastases by engineered T cells., PMID:37399271• ATP signaling and NTPDase in Systemic Lupus Erythematosus (SLE)., PMID:30803848• Heterologous cell-cell interactions: thromboregulation, cerebroprotection and cardioprotection by CD39 (NTPDase-1)., PMID:14675084• Role of CD39 (NTPDase-1) in thromboregulation, cerebroprotection, and cardioprotection., PMID:15852226• CD39/ectonucleoside triphosphate diphosphohydrolase 1 provides myocardial protection during cardiac ischemia/reperfusion injury., PMID:17909107• Ectonucleoside triphosphate diphosphohydrolase 1 and 5'-nucleotidase ecto gene polymorphisms and acute cellular rejection after liver transplantation., PMID:32248630