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抗体药类似物
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Research Grade Davoceticept
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SDS-PAGE
  • Catalog： TD-HV974226
  • Clonality：
  • Application： ELISA, Functional assay, Research in vivo
  • Synonyms： ALPN-202, CD80vIgD-Fc, 2307144-64-3
  • 规格：
    询价
  • 价格：
    ¥100ug
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  • Catalog No.
    TD-HV974226
  • Description
    Davoceticept(TD-HV974226) is a research-grade recombinant antibody targetingCD1. Produced in mammalian cells with native-like glycosylation.HighlightsResearch Grade— For PK/PD studies, assay development, and ADA research.Native Glycosylation— Mammalian expression ensures native-like patterns.
  • Species reactivity
    Human
  • Applications
    ELISA, Functional assay, Research in vivo
  • Isotype
    Fusion - [CD80 (B7-1, CD28LG1) fragment (1-107)]2 - IGHG1 Fc (Fragment constant)
  • Target
    B7-H1, Programmed cell death 1 ligand 1, PDCD1 ligand 1, PDCD1L1, B7 homolog 1, PDCD1LG1, PDL1, hPD-L1, Programmed death ligand 1, B7H1, PD-L1, CD274, CD28, TP44, T-cell-specific surface glycoprotein CD28, CD152, Cytotoxic T-lymphocyte protein 4, CTLA-4, CTLA4, Cytotoxic T-lymphocyte-associated antigen 4
  • Endotoxin level
    Please contact the lab for this information.
  • Purity
    >95% purity as determined by SDS-PAGE.
  • Purification
    Protein A/G purified from cell culture supernatant.
  • Accession
    Q9NZQ7 & P10747 & P16410
  • Form
    Liquid
  • Storage buffer
    0.01M PBS, pH 7.4.Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
  • Stability and Storage
    Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
  • Alternate Names
    ALPN-202, CD80vIgD-Fc, 2307144-64-3
  • Background
    Davoceticept (ALPN-202; CD80 vIgD-Fc) is a variant CD80 vIgD-Fc fusion protein targeting CTLA-4 and PD-L1. Davoceticept consists of the (1-107) fragment of CD80 linked to IGHG1 Fc via a peptidyl linker. The expression system of Davoceticept is usually CHO (Chinese Hamster Ovary) cells.
  • Caption
    SDS-PAGE for Research Grade Davoceticept
  • Note
    For research use only. Not suitable for clinical or therapeutic use.