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Research Grade Acasunlimab
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Bioactivity
SDS-PAGE
  • Catalog： TD-HV974136
  • Clonality： Monoclonal
  • Application： ELISA, Bioactivity: FACS, Functional assay, Research in vivo
  • Synonyms： Bispecific, BNT-311, DuoBody-PD-L1x4-1BB, GEN-1046, 2253937-12-9
  • 规格：
    询价
  • 价格：
    ¥100ug
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  • Catalog No.
    TD-HV974136
  • Description
    Acasunlimab(TD-HV974136) is a research-grade recombinant antibody targetingCD1. Produced in mammalian cells with native-like glycosylation.HighlightsResearch Grade— For PK/PD studies, assay development, and ADA research.Native Glycosylation— Mammalian expression ensures native-like patterns.
  • Species reactivity
    Human
  • Applications
    ELISA, Bioactivity: FACS, Functional assay, Research in vivo
  • Host species
    Humanized
  • Isotype
    IgG1;Lambda;Kappa
  • Clonality
    Monoclonal
  • Target
    B7-H1, Programmed cell death 1 ligand 1, PDCD1 ligand 1, PDCD1L1, B7 homolog 1, PDCD1LG1, PDL1, hPD-L1, Programmed death ligand 1, B7H1, PD-L1, CD274, Tumor necrosis factor receptor superfamily member 9, CD137, 4-1BB ligand receptor, CDw137, TNFRSF9, T-cell antigen ILA, T-cell antigen 4-1BB homolog, ILA
  • Endotoxin level
    Please contact the lab for this information.
  • Purity
    >95% purity as determined by SDS-PAGE.
  • Purification
    Protein A/G purified from cell culture supernatant.
  • Accession
    Q9NZQ7 & Q07011
  • Form
    Liquid
  • Storage buffer
    0.01M PBS, pH 7.4.Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
  • Stability and Storage
    Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
  • Alternate Names
    Bispecific, BNT-311, DuoBody-PD-L1x4-1BB, GEN-1046, 2253937-12-9
  • Background
    Acasunlimab (GEN1046) is a bispecific antibody (bsAb) targeting PD-L1 and 4-1BB. Acasunlimab enhances T-cell and NK-cell function through conditional 4-1BB stimulation while constitutively blocking the PD-1/PD-L1 inhibitory axis. Acasunlimab can be used in research of cancer.
  • Caption
    Detects CD137/TNFRSF9/4-1BB in indirect ELISAs. ### Detects CD274/PD-L1/B7-H1 in indirect ELISAs.　　|　SDS-PAGE for Research Grade Acasunlimab.
  • Note
    For research use only. Not suitable for clinical or therapeutic use.