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抗体药类似物
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Research Grade Samrotamab
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Bioactivity
SDS-PAGE
  • Catalog： TD-HV777016
  • Clonality： Monoclonal
  • Application： ELISA, Bioactivity: FACS, Functional assay, Research in vivo
  • Synonyms： ABBV-085, PR-1498487-MMAE, PR-1498487, Samrotamabvedotin, 2052591-32-7
  • 规格：
    询价
  • 价格：
    ¥100ug
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  • Catalog No.
    TD-HV777016
  • Description
    Samrotamab(TD-HV777016) is a research-grade recombinant antibody targetingLeucine-rich repeat protein induced by beta-amyloid homolog. Produced in mammalian cells with native-like glycosylation.HighlightsResearch Grade— For PK/PD studies, assay development, and ADA research.Native Glycosylation— Mammalian expression ensures native-like patterns.
  • Species reactivity
    Human
  • Applications
    ELISA, Bioactivity: FACS, Functional assay, Research in vivo
  • Host species
    Humanized
  • Isotype
    IgG1-kappa
  • Clonality
    Monoclonal
  • Target
    Leucine-rich repeat protein induced by beta-amyloid homolog, LRRC15, Leucine-rich repeat-containing protein 15, LIB, hLib
  • Endotoxin level
    Please contact the lab for this information.
  • Purity
    >95% purity as determined by SDS-PAGE.
  • Purification
    Protein A/G purified from cell culture supernatant.
  • Accession
    Q8TF66
  • Form
    Liquid
  • Storage buffer
    0.01M PBS, pH 7.4.Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
  • Stability and Storage
    Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
  • Alternate Names
    ABBV-085, PR-1498487-MMAE, PR-1498487, Samrotamabvedotin, 2052591-32-7
  • Background
    Samrotamab is a humanized IgG1-κ chimeric antibody targeting LRRC15.• A novel member of the leucine-rich repeat superfamily induced in rat astrocytes by beta-amyloid., PMID:11785964• Mediators of inflammation and regeneration., PMID:21677081• Lib, transcriptionally induced in senile plaque-associated astrocytes, promotes glial migration through extracellular matrix., PMID:16098915• High lib mRNA expression in breast carcinomas., PMID:15368894
  • Caption
    SEC-HPLC detection for Research Grade Samrotamab.　　|　SDS-PAGE for Research Grade Samrotamab.
  • Note
    For research use only. Not suitable for clinical or therapeutic use.