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抗体药类似物
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Research Grade Cevostamab
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SDS-PAGE
Bioactivity
  • Catalog： TD-HV698016
  • Clonality： Monoclonal
  • Application： ELISA, Bioactivity: FACS, Functional assay, Research in vivo
  • Synonyms： Bispecific, BFCR-4350-A, BFCR-4350A, RG-6160, RO-7187797, 2249888-53-5
  • 规格：
    询价
  • 价格：
    ¥100ug
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  • Catalog No.
    TD-HV698016
  • Description
    Cevostamab(TD-HV698016) is a research-grade recombinant antibody targetingCD307. Produced in mammalian cells with native-like glycosylation.HighlightsResearch Grade— For PK/PD studies, assay development, and ADA research.Native Glycosylation— Mammalian expression ensures native-like patterns.
  • Species reactivity
    Human
  • Applications
    ELISA, Bioactivity: FACS, Functional assay, Research in vivo
  • Host species
    Humanized
  • Isotype
    IgG1-kappa
  • Clonality
    Monoclonal
  • Target
    FcRL5, FCRH5, FCRL5, Fc receptor homolog 5, FcRH5, CD307e, FcR-like protein 5, IRTA2, Immune receptor translocation-associated protein 2, BXMAS1, Fc receptor-like protein 5, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain
  • Endotoxin level
    Please contact the lab for this information.
  • Purity
    >95% purity as determined by SDS-PAGE.
  • Purification
    Protein A/G purified from cell culture supernatant.
  • Accession
    Q96RD9 & P07766
  • Form
    Liquid
  • Storage buffer
    0.01M PBS, pH 7.4.Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
  • Stability and Storage
    Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
  • Alternate Names
    Bispecific, BFCR-4350-A, BFCR-4350A, RG-6160, RO-7187797, 2249888-53-5
  • Background
    Cevostamab (BFCR4350A; RG6160; RO7187797) is a humanized IgG1-based BsAb that targets membrane-proximal extracellular domain of FcRH5 on multiple myeloma (MM) cells as well as CD3 on T cells. Moreover, Cevostamab facilitates efficient synapse formation, improves killing activity of T cells against MM tumor cells.
  • Caption
    SDS-PAGE for Research Grade Cevostamab.　　|　SEC-HPLC detection for Research Grade Cevostamab.
  • Note
    For research use only. Not suitable for clinical or therapeutic use.