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抗体药类似物
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Research Grade Obrindatamab
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SDS-PAGE
Bioactivity
Western blot
  • Catalog： TD-HV612046
  • Clonality： Monoclonal
  • Application： ELISA, Bioactivity: FACS, Functional assay, Research in vivo
  • Synonyms： Bispecific, MGD009, RES281M1.1, hBRCA84D-hXR32-MP3M1.1, 2069959-72-2
  • 规格：
    询价
  • 价格：
    ¥100ug
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  • Catalog No.
    TD-HV612046
  • Description
    Obrindatamab(TD-HV612046) is a research-grade recombinant antibody targetingCD276. Produced in mammalian cells with native-like glycosylation.HighlightsResearch Grade— For PK/PD studies, assay development, and ADA research.Native Glycosylation— Mammalian expression ensures native-like patterns.
  • Species reactivity
    Human
  • Applications
    ELISA, Bioactivity: FACS, Functional assay, Research in vivo
  • Host species
    Humanized
  • Isotype
    scFv with Domain Crossover, Kappa;Lambda
  • Clonality
    Monoclonal
  • Target
    CD276, B7-H3, Costimulatory molecule, B7H3, 4Ig-B7-H3, B7 homolog 3, CD276 antigen, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain
  • Endotoxin level
    Please contact the lab for this information.
  • Purity
    >95% purity as determined by SDS-PAGE.
  • Purification
    Protein A/G purified from cell culture supernatant.
  • Accession
    Q5ZPR3 & P07766
  • Form
    Liquid
  • Storage buffer
    0.01M PBS, pH 7.4.Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
  • Stability and Storage
    Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
  • Alternate Names
    Bispecific, MGD009, RES281M1.1, hBRCA84D-hXR32-MP3M1.1, 2069959-72-2
  • Background
    Obrindatamab is a humanized anti-B7-H3/CD3 bispecific antibody. Obrindatamab binds to B7-H3 and CD3, thereby mediating redirected cytotoxic T-lymphocyte (CTL) activity against B7-H3-expressing cancer cells. Obrindatamab can be used in research of cancer.
  • Caption
    SDS-PAGE for Research Grade Obrindatamab　　|　Detects CD276 in indirect ELISAs. ### Detects CD3E in indirect ELISAs. ### Detects CD276 in indirect ELISA. ### Detects Recombinant Human CD276 Protein, C-His (Cat No.:HV612011) in indirect ELISA.　　|　Western blot analysis was performed using anti-CD276 monoclonal antibody at 1ug/mL on various samples.Lane 1:recombinant human CD276 (Catalog No:TD-HV612011)Lane 2:negative control
  • Note
    For research use only. Not suitable for clinical or therapeutic use.