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抗体药类似物
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Research Grade Enoticumab
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SEC-HPLC
Bioactivity
SDS-PAGE
  • Catalog： TD-HV571026
  • Clonality： Monoclonal
  • Application： ELISA, Bioactivity: FACS, Functional assay, Research in vivo
  • Synonyms： REGN-421, SAR153192, 1192578-27-0
  • 规格：
    询价
  • 价格：
    ¥100ug
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参考文献
  • Catalog No.
    TD-HV571026
  • Description
    Enoticumab(TD-HV571026) is a research-grade recombinant antibody targetingDelta-like protein 4. Produced in mammalian cells with native-like glycosylation.HighlightsResearch Grade— For PK/PD studies, assay development, and ADA research.Native Glycosylation— Mammalian expression ensures native-like patterns.
  • Species reactivity
    Human
  • Applications
    ELISA, Bioactivity: FACS, Functional assay, Research in vivo
  • Host species
    Human
  • Isotype
    IgG1-kappa
  • Clonality
    Monoclonal
  • Target
    Delta-like protein 4, Drosophila Delta homolog 4, Delta4, DLL4
  • Endotoxin level
    Please contact the lab for this information.
  • Purity
    >95% purity as determined by SDS-PAGE.
  • Purification
    Protein A/G purified from cell culture supernatant.
  • Accession
    Q9NR61
  • Form
    Liquid
  • Storage buffer
    0.01M PBS, pH 7.4.Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
  • Stability and Storage
    Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
  • Alternate Names
    REGN-421, SAR153192, 1192578-27-0
  • Background
    Demcizumab (OMP 21M18) is an anti-DLL4 monoclonal antibody. Demcizumab is a potent inhibitor of the Notch pathway. Demcizumab alone or in combination with chemotherapy is effective in various cancer models.
  • Caption
    SEC-HPLC detection for Research Grade Enoticumab.　　|　Detects DLL4 in indirect ELISAs.　　|　SDS-PAGE for Research Grade Enoticumab.　　|　Western blot analysis was performed using anti-DLL4 monoclonal antibody at 1ug/mL on various samples.Lane 1:recombinant human DLL4 (Catalog No:TD-HV571011)Lane 2:negative control
  • Note
    For research use only. Not suitable for clinical or therapeutic use.