Efaprinermin Alfa(TD-HV475026) is a research-grade recombinant antibody targetingCD357. Produced in mammalian cells with native-like glycosylation.HighlightsResearch Grade— For PK/PD studies, assay development, and ADA research.Native Glycosylation— Mammalian expression ensures native-like patterns.
Species reactivity
Human
Applications
ELISA, Functional assay, Research in vivo
Isotype
Fusion - [TNFSF18 (TNF superfamily member 18, AITRL, TL6, GITRL)]2 - IGHG1 Fc (Fragment constant)
Target
Activation-inducible TNFR family receptor, GITR, TNFRSF18, CD357, Tumor necrosis factor receptor superfamily member 18, AITR, Glucocorticoid-induced TNFR-related protein
Endotoxin level
Please contact the lab for this information.
Purity
>95% purity as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9Y5U5
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names
OMP-336B11, 2102200-64-4
Background
Efavaleukin alfa (AMG592) is a human monoclonal antibody. Efavaleukin alfa is composed of the IGHG1 Fc fragment fused to IL-2. The expression system of Efavaleukin alfa is usually CHO (Chinese Hamster Ovary) cells.
Caption
Detects CD357/TNFRSF18/GITR in indirect ELISAs. | SDS-PAGE for Research Grade Efaprinermin Alfa
Note
For research use only. Not suitable for clinical or therapeutic use.