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抗体药类似物
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Research Grade Vanucizumab
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Bioactivity
SEC-HPLC
Flow CytoMetry
  • Catalog： TD-HT073026
  • Clonality： Monoclonal
  • Application： ELISA, Bioactivity: FACS, Functional assay, Research in vivo
  • Synonyms： Bispecific, RG-7221, RG7221, RO5520985, 1448221-05-3
  • 规格：
    询价
  • 价格：
    ¥100ug
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  • Catalog No.
    TD-HT073026
  • Description
    Vanucizumab(TD-HT073026) is a research-grade recombinant antibody targetingVascular endothelial growth factor A. Produced in mammalian cells with native-like glycosylation.HighlightsResearch Grade— For PK/PD studies, assay development, and ADA research.Native Glycosylation— Mammalian expression ensures native-like patterns.
  • Species reactivity
    Human
  • Applications
    ELISA, Bioactivity: FACS, Functional assay, Research in vivo
  • Host species
    Humanized
  • Isotype
    human IgG1 - kappa - lambda with half-IG VL-CH1/VH-CK crossover
  • Clonality
    Monoclonal
  • Target
    Vascular endothelial growth factor A, VPF, VEGFA, VEGF, Vascular permeability factor, VEGF-A, ANG-2, ANGPT2, Angiopoietin-2
  • Endotoxin level
    Please contact the lab for this information.
  • Purity
    >95% purity as determined by SDS-PAGE.
  • Purification
    Protein A/G purified from cell culture supernatant.
  • Accession
    P15692 & O15123
  • Form
    Liquid
  • Storage buffer
    0.01M PBS, pH 7.4.Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
  • Stability and Storage
    Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
  • Alternate Names
    Bispecific, RG-7221, RG7221, RO5520985, 1448221-05-3
  • Background
    Zifibancimig is an anti-VEGFA/ANGPT2 IgG1κ monoclonal antibody.
  • Caption
    Detects Human VEGFA in indirect ELISAs. ### Detects Human ANGPT2 in indirect ELISAs.　　|　SEC-HPLC detection for Research Grade Vanucizumab.　　|　Flow-cytometry using FITC anti-human VEGFA&ANGPT2 antibody. U87 cells were fixed and permeabilized, then stained with an irrelevant antibody (Blue Histogram) or an FITC anti-human VEGFA&ANGPT2 monoclonal antibody (Catalog: HT073026, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.
  • Note
    For research use only. Not suitable for clinical or therapeutic use.