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Research Grade Mapatumumab
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Bioactivity
SDS-PAGE
Western blot
  • Catalog： TD-HT017016
  • Clonality： Monoclonal
  • Application： ELISA, Bioactivity: FACS, Functional assay, Research in vivo
  • Synonyms： HGS-ETR1, TRM-1, 658052-09-6
  • 规格：
    询价
  • 价格：
    ¥100ug
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  • Catalog No.
    TD-HT017016
  • Description
    Mapatumumab(TD-HT017016) is a research-grade recombinant antibody targetingCD261. Produced in mammalian cells with native-like glycosylation.HighlightsResearch Grade— For PK/PD studies, assay development, and ADA research.Native Glycosylation— Mammalian expression ensures native-like patterns.
  • Species reactivity
    Human
  • Applications
    ELISA, Bioactivity: FACS, Functional assay, Research in vivo
  • Host species
    Human
  • Isotype
    IgG1-nd
  • Clonality
    Monoclonal
  • Target
    TNF-related apoptosis-inducing ligand receptor 1, APO2, Death receptor 4, TRAIL receptor 1, TRAIL-R1, CD261, DR4, TRAILR1, TNFRSF10A, Tumor necrosis factor receptor superfamily member 10A
  • Endotoxin level
    Please contact the lab for this information.
  • Purity
    >95% purity as determined by SDS-PAGE.
  • Purification
    Protein A/G purified from cell culture supernatant.
  • Accession
    O00220
  • Form
    Liquid
  • Storage buffer
    0.01M PBS, pH 7.4.Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
  • Stability and Storage
    Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
  • Alternate Names
    HGS-ETR1, TRM-1, 658052-09-6
  • Background
    Mapatumumab (HGS-ETR1) is a fully human IgG1 agonistic monoclonal antibody that targets tumor necrosis factor-related apoptosis-inducing ligand receptor 1 (TRAIL-R1). Mapatumumab can be used for the research of cancer.
  • Caption
    SEC-HPLC detection for Research Grade Mapatumumab.　　|　SDS-PAGE for Research Grade Mapatumumab.　　|　Western blot analysis was performed using anti-CD261/TNFRSF10A monoclonal antibody at 1ug/mL on various samples.Lane 1:recombinant human CD261/TNFRSF10A (Catalog No:TD-HT017011)Lane 2:negative control
  • Note
    For research use only. Not suitable for clinical or therapeutic use.