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抗体药类似物
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Research Grade Isecarosmab
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SDS-PAGE
  • Catalog： TD-HP572016
  • Clonality： Monoclonal
  • Application： ELISA, Bioactivity: FACS, Functional assay, Research in vivo
  • Synonyms： Bispecific, M-6495, 2254082-79-4
  • 规格：
    询价
  • 价格：
    ¥100ug
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  • Catalog No.
    TD-HP572016
  • Description
    Isecarosmab(TD-HP572016) is a research-grade recombinant antibody targetingA disintegrin and metalloproteinase with thrombospondin m.... Produced in mammalian cells with native-like glycosylation.HighlightsResearch Grade— For PK/PD studies, assay development, and ADA research.Native Glycosylation— Mammalian expression ensures native-like patterns.
  • Species reactivity
    Human
  • Applications
    ELISA, Bioactivity: FACS, Functional assay, Research in vivo
  • Host species
    Humanized(Lama/glama)
  • Isotype
    VH-VH'
  • Clonality
    Monoclonal
  • Target
    A disintegrin and metalloproteinase with thrombospondin motifs 5, ADAM-TS 5, ADAM-TS5, ADAMTS-5, EC:3.4.24.-, A disintegrin and metalloproteinase with thrombospondin motifs 11, ADAM-TS 11, ADAMTS-11, ADMP-2, Aggrecanase-2, ADAMTS5, ALB, Albumin
  • Endotoxin level
    Please contact the lab for this information.
  • Purity
    >95% purity as determined by SDS-PAGE.
  • Purification
    Protein A/G purified from cell culture supernatant.
  • Accession
    Q9UNA0 & P02768
  • Form
    Liquid
  • Storage buffer
    0.01M PBS, pH 7.4.Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
  • Stability and Storage
    Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
  • Alternate Names
    Bispecific, M-6495, 2254082-79-4
  • Background
    Isecarosmab (M-6495) is an anti-ADAMTS monoclonal antibody (mAb) with a KD value of 3.65 pM. Isecarosmab has chondroprotective and anti-inflammatory activities. Isecarosmab can bind albumin to extend plasma half-life.
  • Caption
    SDS-PAGE for Research Grade Isecarosmab.
  • Note
    For research use only. Not suitable for clinical or therapeutic use.