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抗体药类似物
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Research Grade Livmoniplimab
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Bioactivity
  • Catalog： TD-HF977036
  • Clonality： Monoclonal
  • Application： ELISA, Bioactivity: FACS, Functional assay, Research in vivo
  • Synonyms： Bispecific, ABBV-151, ARGX-115, MHG-8, MHGARP-8, PR-17628442412004-88-5
  • 规格：
    询价
  • 价格：
    ¥100ug
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  • Catalog No.
    TD-HF977036
  • Description
    Livmoniplimab(TD-HF977036) is a research-grade recombinant antibody targetingTransforming growth factor beta-1 proprotein. Produced in mammalian cells with native-like glycosylation.HighlightsResearch Grade— For PK/PD studies, assay development, and ADA research.Native Glycosylation— Mammalian expression ensures native-like patterns.
  • Species reactivity
    Human
  • Applications
    ELISA, Bioactivity: FACS, Functional assay, Research in vivo
  • Host species
    Humanized
  • Isotype
    IgG4-kappa
  • Clonality
    Monoclonal
  • Target
    Transforming growth factor beta-1 proprotein, LAP, TGF-beta-1, TGFB1, TGFB, GARP, Leucine-rich repeat-containing protein 32, Glycoprotein A repetitions predominant, D11S833E, Garpin, Transforming growth factor beta activator LRRC32, LRRC32
  • Endotoxin level
    Please contact the lab for this information.
  • Purity
    >95% purity as determined by SDS-PAGE.
  • Purification
    Protein A/G purified from cell culture supernatant.
  • Accession
    P01137 & Q14392
  • Form
    Liquid
  • Storage buffer
    0.01M PBS, pH 7.4.Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
  • Stability and Storage
    Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
  • Alternate Names
    Bispecific, ABBV-151, ARGX-115, MHG-8, MHGARP-8, PR-17628442412004-88-5
  • Background
    Livmoniplimab (ABBV-151) is a monoclonal antibody against GARP/TGF-β1 that can inhibit the release of active TGF-β1. Livmoniplimab has anti-tumor activity in colon cancer mice. Livmoniplimab can be used for the study of locally advanced or metastatic solid tumors.
  • Caption
    SEC-HPLC detection for Research Grade Livmoniplimab.
  • Note
    For research use only. Not suitable for clinical or therapeutic use.