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Research Grade Fresolimumab
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SEC-HPLC
Bioactivity
SDS-PAGE
  • Catalog： TD-HF977016
  • Clonality： Monoclonal
  • Application： ELISA, Bioactivity: FACS, Functional assay, Research in vivo
  • Synonyms： GC-1008, 948564-73-6
  • 规格：
    询价
  • 价格：
    ¥100ug
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  • Catalog No.
    TD-HF977016
  • Description
    Research Grade Fresolimumab(TD-HF977016) is ahuman monoclonalantibody detectingTransforming growth factor beta-1 proproteininELISA, Bioactivity: FACS, Functional assay, Research in vivo. Suitable forHuman.HighlightsMulti-Application— Validated across multiple applications.
  • Species reactivity
    Human
  • Applications
    ELISA, Bioactivity: FACS, Functional assay, Research in vivo
  • Host species
    Human
  • Isotype
    IgG4-kappa
  • Species
    Human
  • Clonality
    Monoclonal
  • Target
    Transforming growth factor beta-1 proprotein, Latency-associated peptide, LAP, Transforming growth factor beta-1, TGF-beta-1, TGFB1, Transforming growth factor beta-2 proprotein, Cetermin, Glioblastoma-derived T-cell suppressor factor, G-TSF, Latency-associated peptide, LAP, Transforming growth factor beta-2, TGF-beta-2, TGFB2, Transforming growth factor beta-3 proprotein, Latency-associated peptide, LAP, Transforming growth factor beta-3, TGF-beta-3, TGFB3
  • Endotoxin level
    Please contact with the lab for this information.
  • Purity
    >95% as determined by SDS-PAGE.
  • Purification
    Protein A/G purified from cell culture supernatant.
  • Accession
    P01137, P61812, P10600
  • Form
    Liquid
  • Storage buffer
    0.01M PBS, pH 7.4.Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
  • Stability and Storage
    Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
  • Alternate Names
    GC-1008, 948564-73-6
  • Background
    Fresolimumab (GC1008) is a human monoclonal antibody against TGF-β that neutralizes all mammalian active subtypes of TGF-β. The binding affinity of Fresolimumab to TGF-β2 is 1.8 nM. Fresolimumab radiolabeled with 89Zr can be used for PET analysis of TGF-β expression, antibody uptake and organ distribution. Fresolimumab can be used in the study of cancer, osteogenesis imperfecta, fibrosis and kidney disease.
  • Caption
    SEC-HPLC detection for Research Grade Fresolimumab.　　|　Detects Human TGFB1/TGF-beta-1 in indirect ELISAs.　　|　SDS-PAGE for Research Grade Fresolimumab.
  • Note
    For research use only. Not suitable for clinical or therapeutic use.