TD-HF974016

Apolizumab(TD-HF974016) is a research-grade recombinant antibody targetingHLA class II histocompatibility antigen. Produced in mammalian cells with native-like glycosylation.HighlightsResearch Grade— For PK/PD studies, assay development, and ADA research.Native Glycosylation— Mammalian expression ensures native-like patterns.

Human

ELISA, Bioactivity: FACS, Functional assay, Research in vivo

Humanized

IgG1-nd

Monoclonal

HLA class II histocompatibility antigen, DRB1 beta chain, Human leukocyte antigen DRB1, HLA-DRB1

Please contact the lab for this information.

>95% purity as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

P01911

Liquid

0.01M PBS, pH 7.4.Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.

Hu1D10, 267227-08-7

Apolizumab (Hu1D10) is a humanized monoclonal anti-Human leukocyte antigen-DR beta-chain antibody. Apolizumab can mediate apoptosis of chronic lymphocytic leukemia (CLL) cells in vitro.• HLA common and well-documented alleles in China., PMID:30073798• Association of Human Leukocyte Antigen (HLA) class II (DRB1andDQB1) alleles and haplotypes with Rheumatoid Arthritis in Sudanese patients., PMID:37426636• Human-leukocyte antigen class II genes in early-onset obsessive-compulsive disorder., PMID:28562177• Association between human leukocyte antigen class II-DR-DQ and narcolepsy: a case control study., PMID:39150697• Human leukocyte antigen class II (DRB1 and DQB1) alleles and haplotypes frequencies in patients with pemphigus vulgaris among the Serbian population., PMID:27072514• Sarcoidosis and human leukocyte antigen class I and II genes: it takes two to tango?, PMID:15003948• Amino acid polymorphisms in human histocompatibility leukocyte antigen class II and proinsulin epitope have impacts on type 1 diabetes mellitus induced by immune-checkpoint inhibitors., PMID:37114039• A new strategy for systematically classifying HLA alleles into serological specificities., PMID:35538616• Diagnosis of sarcoidosis., PMID:18664976• Human leukocyte antigen class II alleles in Caucasian women with primary biliary cirrhosis., PMID:15713222

SEC-HPLC detection for Research Grade Apolizumab.　　|　SDS-PAGE for Research Grade Apolizumab

For research use only. Not suitable for clinical or therapeutic use.