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抗体药类似物
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Research Grade Duvakitug
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SDS-PAGE
  • Catalog： TD-HF526076
  • Clonality： Monoclonal
  • Application： ELISA, Bioactivity: FACS, Functional assay, Research in vivo
  • Synonyms： 2750005-84-4
  • 规格：
    询价
  • 价格：
    ¥100ug
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  • Catalog No.
    TD-HF526076
  • Description
    Duvakitug(TD-HF526076) is a research-grade recombinant antibody targetingTNFSF15. Produced in mammalian cells with native-like glycosylation.HighlightsResearch Grade— For PK/PD studies, assay development, and ADA research.Native Glycosylation— Mammalian expression ensures native-like patterns.
  • Species reactivity
    Human
  • Applications
    ELISA, Bioactivity: FACS, Functional assay, Research in vivo
  • Host species
    Human
  • Isotype
    IgG1-lambda
  • Clonality
    Monoclonal
  • Target
    TNFSF15, Vascular endothelial cell growth inhibitor, VEGI, TL1, TNF ligand-related molecule 1, Tumor necrosis factor ligand superfamily member 15
  • Endotoxin level
    Please contact the lab for this information.
  • Purity
    >95% purity as determined by SDS-PAGE.
  • Purification
    Protein A/G purified from cell culture supernatant.
  • Accession
    O95150
  • Form
    Liquid
  • Storage buffer
    0.01M PBS, pH 7.4.Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
  • Stability and Storage
    Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
  • Alternate Names
    2750005-84-4
  • Background
    Duvakitug is a humanized IgG1-λ2 monoclonal antibody targeting to TNFSF15/TL1A. Duvakitug' main expression system is CHOK1SV cells endogenously expressing glutamine synthetase (GS). Duvakitug can be used in the study of Crohn's Disease (CD).• Vascular endothelial growth inhibitor in human cancer (Review)., PMID:19513527• VEGI-192, a new isoform of TNFSF15, specifically eliminates tumor vascular endothelial cells and suppresses tumor growth., PMID:16061878
  • Caption
    SDS-PAGE for Research Grade Duvakitug.
  • Note
    For research use only. Not suitable for clinical or therapeutic use.