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Recombinant Human CD45 / PTD-TPRC Protein (Fc tag)
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Recombinant Human CD45 / PTPRC Protein (Fc tag)
| Product Name: | Recombinant Human CD45 / PTPRC Protein (Fc tag) |
| Cat No.: | TD-TP07637 |
| TargetID: | P08575 |
| Source: | HEK293 Cells |
| Gene Accession Number: | 5788 |
| Peptide Sequence: | Met 1-Lys 414 |
| Tag: | C-Fc |
| Purity: | >85% as determined by SDS-PAGE. |
| Formulation: | Freeze-dried powder |
| Storage Buffer: | Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition: | Aliquot and store at -20℃ to -80℃ for up to 6 months, buffer containing 50% glycerol is recommen |
| Category: | Protein |
| Species Reactivity: | Human |
| Predicted Molecular Mass: | 71.1 kDa |
| Applications: | Positive Control; Immunogen; SDS-PAGE; WB |
| Background: | Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity |
| Size: | 10ug 50ug 100ug 200ug 1mg |
| Synonyms: | B220;CD45;CD45R;GP180;L-CA;LCA;LY5;T200 |
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15% SDS-PAGE Reduced |