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IL-10 Receptor alpha Rabbit pAb
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- Catalog： TD-120162
- Clonality： pAb
- Application： ELISA,IHC-P
- Synonyms：
-
规格：
100μl 50μl
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价格：
¥2080
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IL-10 Receptor alpha Rabbit pAb
| Product Name | IL-10 Receptor alpha Rabbit pAb |
| Gene ID | 3587 |
| SwissProt ID | Q13651 |
| Gene Name | IL10RA |
| Alternative Names | IL10RA; IL10R; Interleukin-10 receptor subunit alpha; IL-10 receptor subunit alpha; IL-10R subunit alpha; IL-10RA; CDw210a; Interleukin-10 receptor subunit 1; IL-10R subunit 1; IL-10R1; CD antigen CD210 |
| Background | The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. |
| Research Field | Immunology |
| Product Categories | Primary antibody |
| Host | Rabbit |
| Reactivity | Human |
| Application | IHC-P |
| Dilution Ratio | IHC: 1/50-1/100 |
| Molecular Weight | - |
| Clonality | Polyclonal Antibody |
| Clonality No. | - |
| Isotype | IgG |
| Immunogen | Fusion protein of human IL10RA |
| Purification | Affinity Purified |
| Conjugation | Unconjugated |
| Modification | Unmodified |
| Form | Liquid |
| Buffer System | pH 7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
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Immunohistochemistry analysis of paraffin-embedded Human tosil using IL-10 Receptor alpha antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. |