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IL-1 Receptor Accessory Protein Rabbit mAb
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IL-1 Receptor Accessory Protein Rabbit mAb
| Product Name | IL-1 Receptor Accessory Protein Rabbit mAb |
| Gene ID | 3556 |
| SwissProt ID | Q9NPH3 |
| Gene Name | IL1RAP |
| Alternative Names | IL-1 Receptor Accessory Protein; IL1R3; C3orf13; IL-1RAcP |
| Background | Interleukin 1 induces synthesis of acute phase and proinflammatory proteins during infection, tissue damage, or stress, by forming a complex at the cell membrane with an interleukin 1 receptor and an accessory protein. This gene encodes the interleukin 1 receptor accessory protein. The protein is a necessary part of the interleukin 1 receptor complex which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in two transcript variants encoding two different isoforms, one membrane-bound and one soluble. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress. |
| Research Field | Immunology |
| Product Categories | Recombinant Rabbit Monoclonal antibody |
| Host | Rabbit |
| Reactivity | Human |
| Application | WB,IP |
| Dilution Ratio | WB: 1/500-1/1000 IP: 1/20 |
| Molecular Weight | Calculated MW: 65 kDa; Observed MW: 78 kDa |
| Clonality | Monoclonal Antibody |
| Clonality No. | R05-3B8 |
| Isotype | IgG |
| Immunogen | Recombinant protein of human IL-1RAcP |
| Purification | Affinity Purified |
| Conjugation | Unconjugated |
| Modification | Unmodified |
| Form | Liquid |
| Buffer System | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
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Western blot analysis of IL-1RAcP in HL-60, U251, U87-MG lysates using IL-1 Receptor Accessory Protein antibody. |