| Catalog No. |
TD-RP10874 |
| Synonyms |
Exendin4exenatide; Byetta |
| Description |
Exendin-4 is a 39-amino acid peptide amide. Exendin-4, like Exendin-3, stimulates an increase in acinar cAMP without stimulating the release of amylase. Exendin-4 is a long-acting potent agonist of the glucagon-like peptide 1 (GLP-1). Exendin-4 is the active component of Byetta (exenatide) injection, which may improve glycemic control in people with type 2 diabetes mellitus and has the potential to reduce plasma glucose at least partly by a delay in gastric emptying as well as by reducing calorie intake. Exendin-4 enhances glucose-dependent insulin secretion by the pancreatic β-cell and suppresses inappropriately elevated glucagon secretion. |
| Cas No |
141758-74-9 |
| Sequence |
{HIS}{GLY}{GLU}{GLY}{THR}{PHE}{THR}{SER}{ASP}{LEU}{SER}{LYS}{GLN}{MET}{GLU}{GLU}{GLU}{ALA}{VAL}{ARG}{LEU}{PHE}{ILE}{GLU}{TRP}{LEU}{LYS}{ASN}{GLY}{GLY}{PRO}{SER}{SER}{GLY}{ALA}{PRO}{PRO}{PRO}{SER} |
| Sequence Shortening |
HGEGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS |
| Molecular Formula |
C₁₈₄H₂₈₂N₅₀O₆₀S |
| C Terminal |
Amidation |
| Molecular Weight |
4186.66 |
| Purity |
> 95% |
| Solubility |
Soluble in Ultrapure water under 1mg/ml |
| Form |
Lyophilized |
| Storage |
Store the peptide at -20°C. |
| Note |
This peptide interacts with exendin receptor to increase pancreatic acinar cAMP. It has no secretagogue activity and does not bind to VIP receptors. |
抗体
试剂盒
多肽
蛋白
组织芯片
定制服务咨询