Cyclo(Arg-Gly-Asp-(D-Phe)-Glu)
描 述: Cyclo(Arg-Gly-Asp-(D-Phe)-Glu) c(RGDfE) 是一种靶向整合素 αvβ3 的环状 RGD 肽。Cyclo(Arg-Gly-Asp-(D-Phe)-Glu) 通常用于修饰载药纳米颗粒。Cyclo(Arg-Gly-Asp-(D-Phe)-Glu) 常用于癌症研究,如胰腺癌。
CAS号:756500-22-8
单字母: Cyclo(RGD-{d-Phe}-E)
多字母: Cyclo(Arg-Gly-Asp-{d-Phe}-Glu)
分子式: C26H36N8O9
分子量: 604.61
参考文献:
[1]. Kim DH, et al. Deoxycholate bile acid directed synthesis of branched Au nanostructures for near infrared photothermal ablation. Biomaterials. 2015 Jul;56:154-64.
[2]. Sun J , et al. A c(RGDfE) conjugated multi-functional nanomedicine delivery system for targeted pancreatic cancer therapy. J Mater Chem B. 2015 Feb 14;3(6):1049-1058.