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Human Tau 1-441 Protein
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Human Tau 1-441 Protein
| Product Name | Human Tau 1-441 Protein |
| Cat.# | TD-P1005 |
| Size | 50ug |
| Protein Name | TAU |
| Synonym | DDPAC,FTDP-17,MAPT,MSTD,MTBT |
| Uniprot No. | P10636 |
| Expression System | E. Coli |
| Compound Identity | TAU(e1)-his |
| Full Length or Truncated | Full length |
| Molecular Weight | 48.3 kDa |
| Form | freeze-dried powder |
| Storage | -80°C (as supplied) |
| Stability | ≥6 months |
| Purity | ≥80% estimated by SDS-PAGE |
| Supplied in | 1×PBS (pH 7.2) |
| Background | |
| Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimers disease, frontotemporal dementia, and other tauopathies. | |
| SDS-PAGE Validation | |
| 12 % SDS-PAGE | Lane Description |
|
1 2 |
Lane 1: Protein Marker Lane 2:TAU(e1)(1:2 dilution) |